Intermittent fasting (IF) has emerged as a popular strategy for weight management and overall health improvement. However, when addressing women’s hormonal health, the effects of IF can be more complex. Although many women report benefits from intermittent fasting, others may experience adverse effects such as disruptions in progesterone and estrogen balance. Our hormone support supplement, Baseline+, is designed to support hormonal equilibrium, making intermittent fasting a more effective and sustainable practice.
There are several key mechanisms through which intermittent fasting influences female hormones (1)(2). For example, IF may elevate cortisol levels, increasing stress hormones that, when chronically high, can disrupt menstrual cycles, impair digestion, raise blood pressure, and elevate blood sugar. Conversely, intermittent fasting has been shown to improve insulin sensitivity, which is particularly beneficial for women struggling with polycystic ovary syndrome (PCOS) or insulin resistance. Enhanced insulin sensitivity can stabilize blood sugar levels and reduce the risk of metabolic complications. However, because women’s hormone levels fluctuate during the menstrual cycle, prolonged fasting windows can interfere with the natural production of estrogen and progesterone. In addition, extreme fasting may impact thyroid function—a key regulator of metabolism—resulting in symptoms such as fatigue, weight gain, and brain fog.
Balancing the benefits and risks of intermittent fasting is essential. On the one hand, IF can contribute to weight and fat loss, which may further improve hormonal balance by mitigating issues like insulin resistance and estrogen dominance. Fasting may also promote autophagy, a cellular clean-up process that removes damaged cells and encourages regeneration, thereby supporting hormonal health. Moreover, the anti-inflammatory effects of IF can be beneficial for conditions such as PCOS and endometriosis, which are often linked to inflammation and hormonal disturbances. On the other hand, the potential disruption of the menstrual cycle, particularly in women with a history of irregular periods or those who are underweight, remains a significant concern. Extended fasting periods of 16-18 hours could also lead to hormonal imbalances and increased stress.
For those considering intermittent fasting, incorporating Baseline+ into your regimen may offer additional hormonal support. This supplement contains myo-inositol and chromium to help regulate insulin and blood sugar levels, thereby promoting metabolic stability (3). It also features DIM and Vitex, which are instrumental in supporting estrogen balance during fasting (4), as well as adaptogenic herbs that help reduce stress and counteract cortisol spikes. Furthermore, essential vitamins included in Baseline+ assist in regulating hormones, especially on fasting days (5).
“Love Baseline. I have been using for about three years. Helps keep my cycle regulated, less cramps and shorter. Keeps my skin clear. Magic!” – Finessa L.
For best results, it is advisable to begin with a 12-hour fast and adjust gradually as needed. When breaking your fast in the morning, opt for a nutrient-dense, high-protein meal, and ensure that subsequent meals within your eating window maintain similar nutritional quality. Avoid scheduling fasting on days with intense workouts, and always monitor your symptoms closely. Should you experience irregular periods or any adverse effects, consider reducing your fasting duration. To further support your hormonal balance while practicing intermittent fasting, incorporate Baseline+.
The contents of this blog should not be taken as medical advice. It is not intended to diagnose, treat, cure, or prevent any health problem-nor is it intended to replace the advice of a physician. Always consult your physician or qualified health professional on any matters regarding your health. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Sources:
(1) Effect of Intermittent Fasting on Reproductive Hormone Levels in Females and Males: A Review of Human Trials – PMC
(2) Effects of Intermittent Fasting on the Circulating Levels and Circadian Rhythms of Hormones – PMC
(3) Myo-inositol for insulin resistance, metabolic syndrome, polycystic ovary syndrome and gestational diabetes – PMC
(4) 3,3′-Diindolylmethane Modulates Estrogen Metabolism in Patients with Thyroid Proliferative Disease: A Pilot Study – PMC
(5) The effect of adaptogenic plants on stress: A systematic review and meta-analysis – ScienceDirect
